Short CV (for a full CV click here)

CURRENT POSITIONS & AFFILIATIONS:

Professor of Biology (2010 - ) University of New Brunswick, Department of Biology, Fredericton, New Brunswick, Canada

Director of Education and Outreach (2011 - ) Center for Evolution and Cancer, University of California San Francisco, USA

External Faculty (2011 - )  Center for Evolution and Cancer, University of California at San Francisco, USA

Adjunct Faculty (2002 - ) University of Arizona, Department of Ecology and Evolutionary Biology, Tucson, USA

RECENT PAPERS (for other papers and downloads go to Publications):

Nedelcu AM. Volvox. In World Book Encyclopedia. World Book Publishing (submitted)

Nedelcu AM and Caulin AF. The evolution of cancer suppressor mechanisms. In Maley CC (ed) "Frontiers of Evolution in Cancer". Springer (submitted).

Sprouffske K, Aktipis CA,  Radich JP, Carroll M, Nedelcu AM, and Maley CC. An evolutionary explanation for the presence of cancer non-stem cells in neoplasms. Evolutionary Applications 6:92-101.

Lang BF and AM Nedelcu. 2012. Plastid genomes of algae. In Bock R and Knoop V (eds) “Genomics of Chloroplasts and Mitochondria”. Advances in Photosynthesis and Respiration Series. Vol 35. pp. 59-87. Springer.

Burger G and AM Nedelcu.  2012. Mitochondrial genomes of algae. In Bock R and Knoop V (eds) “Genomics of Chloroplasts and Mitochondria”. Advances in Photosynthesis and Respiration Series. Vol. 35. pp. 127-157. Springer.

Nedelcu AM. 2012. Evolution of multicellularity. In: eLS (Encyclopedia of Life Sciences) 2012, John Wiley & Sons, Ltd: Chichester http://www.els.net/ [DOI:10.1002/9780470015902.a0023665].

Nedelcu AM. 2012. On the evolution of self during the transition to multicellularity.  In Carlos Lopez-Larrea (ed) Self and "Non-self”. pp. 14-30. Landes Biosciences.

Nedelcu AM and RE Michod.  2011. Molecular mechanisms of life history trade-offs and the evolution of multicellular complexity in volvocalean green algae. In Flatt T and Heyland A (eds) “Mechanisms of Life History Evolution: The Genetics and Physiology of Life History traits and Trade-Offs”. pp. 271-283. Oxford University Press.

Nedelcu AM, Driscoll WW, Durand PM, Herron M, and Rashidi E. 2011. On the paradigm of altruistic suicide in the unicellular world. Evolution 65:3-20.

Prochnik SE, Umen J, Nedelcu AM et al. 2010. Genomic analysis of organismal complexity in the multicellular green alga Volvox carteri. Science 329:223-226.

Nedelcu AM. 2009. Environmentally-induced responses co-opted for reproductive altruism. Biology Letters 5: 805-808.

Nedelcu AM, A Blakney and K Logue. 2009. Functional replacement of a primary metabolic pathway via multiple independent eukaryote-to-eukaryote gene transfers and selective retention. Journal of Evolutionary Biology 22: 1882-1894.

Nedelcu AM. 2009. Comparative genomics of phylogenetically diverse unicellular eukaryotes provide new insights into the genetic basis for the evolution of the programmed cell death machinery. Journal of Molecular Evolution 68: 256-268.

Nedelcu AM, I Miles, K Karol, A Fagir. 2008. Adaptive eukaryote-to eukaryote gene transfer: Stress-related genes of algal origin in the closest unicellular relatives of animals. Journal of Evolutionary Biology 21: 1852-1860.

Michod RE., Bernstein H, Nedelcu AM. 2008. Adaptive Value of Sex in Microbial Pathogens. Infection, Genetics and Evolution 8: 267-285.

Nedelcu AM and C Tan. 2007. Early diversification and complex evolutionary history of the p53 tumor suppressor gene family. Development Genes and Evolution 217: 801-806.

Merchant SS et al (118 authors). 2007. The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science 318: 245-250.

Nedelcu AM. 2006. Evidence for p53-like-mediated stress responses in green algae. FEBS Letters 580: 3013-3017.

Nedelcu AM and RE Michod. 2006. The evolutionary origin of an altruistic gene. Mol. Biol. Evol. 23: 1460-1464.

Nedelcu AM, Borza T, and RW Lee. 2006. A land plant-specific multigene family in the unicellular Mesostigma argues for its close relationship to Streptophyta. Mol. Biol. Evol. 23: 1011-1014.

Michod RE, Y Viossat, CA Solari, M Hurrand and AM Nedelcu. 2006. Life history evolution and the origin of multicellularity. J. Theor. Biol. 239: 257-272.

Nedelcu AM. 2005. Sex as a response to oxidative stress: Stress genes co-opted for sex. Proceedings of Royal Society London B, Biological Sciences 272: 1935-1940.

RECENT PRESENTATIONS (go to Meetings):

Evolutionary vulnerabilities in cancer: Insights from unicellular lineages. 1^st Conference on Evolution and Cancer. Center for Evolution and Cancer. UCSF, San Francisco, USA. 2011

Stress responses and life history evolution in the unicellular world. Workshop on Environmental changes and the evolution of marine ecosystems. French National Agency for Research (ANR) and TARA OCEANS – Atelier de Reflexion Prospective. Stazione Zoologica A. Dohrn, Naples, Italy. 2011.

Co-opting environmentally-induced responses for group advantage. 2010. Biocomplexity XI Workshop. The Evolution of Cooperation: Paradoxes of Collectivity & Individuality. Bloomington, IN, USA.

General acclimation responses co-opted for somatic cell differentiation in Volvox carteri. 2010. 14th International Conference on the Cell and Molecular Biology of Chlamydomonas, Norton, MA, USA.

The genetic basis for the evolution of reproductive altruism. 2009. 12^th Congress of the European Society for Evolutionary Biology (ESEB). Torino, Italy.

The mechanistic basis for the evolution of reproductive altruism. 2009.  The Center for Social Dynamics and Complexity 1^st International Conference: Groups as individuals. Tempe, AZ, USA.

Chlamydomonas as a model-system for programmed cell death research. 2008. 13th International Conference on the Cell and Molecular Biology of Chlamydomonas, Hyeres, France.

To die, or not to die? Programmed cell death in Volvox carteri. 2007. Volvox Symposium, St. Louis, MO, USA

Early evolution of the eukaryotic programmed cell death machinery revealed by comparative genomics. 2007. Annual meeting of the Society for Molecular Biology and Evolution.  Halifax, NS, Canada

p53-like-mediated stress responses in Chlamydomonas and Volvox. 2006. 12^th International Conference on the Cell and Molecular Biology of Chlamydomonas, Portland, Oregon, USA

RECENT FUNDING

National Center for Genome Resources (USA) and the Gordon and Betty Moore Foundation Marine Microbiology Initiative: Transcriptome sequencing of marine eukaryotic algae (Co-PI; with David R. Smith, UBC, Canada) (2011)

NSERC Discovery Grant: The genetic basis for the evolution of altruism during the transition to multicellularity (2008-2013)

NSF: Life-history trade-offs and the evolution of multicellularity (Co-PI; PI: Richard E. Michod, U Arizona, USA) (2008-2009)

NSERC Discovery grant: "An alternative framework for understanding evolutionary transitions: the green algal group as a model-system" (2003-2008)

NSERC RTI Grant: Real-Time PCT Thermal Cycler to Quantify Genes and Gene Expression (Co-PI; with 5 from UNB) (2007)

NSERC Equipment Grant: Refrigerated microfuge to study the evolution of programmed cell death (2006)

NSERC Equipment Grant: Free-radical analyzer to study the evolution of cellular responses to oxidative stress (2005)

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Last updated: November 19, 2012.